Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNE1 | P15382 | 10/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 10/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5990959 | 1.00 | ABCC9 (0.39) | ABCC9LMNAMAPTNPSR1TDP1 | |
| SCHEMBL5989324 | 0.88 | ABCC9 (0.36) | ABCC9TDP1KCNE1KCNQ1KDM4E | |
| SCHEMBL5988487 | 0.83 | ABCC9 (0.40) | ABCC9TDP1KCNE1KCNQ1KDM4E | |
| SCHEMBL5988483 | 0.83 | ABCC9 (0.40) | ABCC9TDP1KCNE1KCNQ1KDM4E | |
| SCHEMBL5989260 | 0.80 | ABCC9 (0.39) | ABCC9TDP1KDM4EABCB1 | |
| SCHEMBL14313878 | 0.79 | TLR3 (0.38) | ABCC9MAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL2887176 | 0.79 | TLR3 (0.38) | ABCC9MAPTNPSR1ALDH1A1MEN1 | |
| SCHEMBL2888950 | 0.78 | KCNA5 (0.42) | MAPTNPC1KCNE1KCNQ1ALDH1A1 | |
| SCHEMBL14313851 | 0.77 | ABCC9 (0.37) | ABCC9LMNAMAPTABCB1CYP1A2 | |
| SCHEMBL5988198 | 0.77 | ABCC9 (0.35) | ABCC9KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1718629-B1 | Benzopyran compounds useful for the treatment of arrhytmia | NISSAN CHEMICAL IND LTD (JP) | 2012-12-26 | — | — | EP | disclosed |
| EP-1718629-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR THE TREATMENT OF ARRHYTMIA | Nissan Chemical Industries, Ltd. (JP) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005080368-A2 | BENZOPYRAN COMPOUND USEFUL FOR THE TREATMENT OF ARRHYTMIA | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-01 | — | — | WO | disclosed |