Pyruvate

Pyruvate

SCHEMBL599108

CC(=O)C(=O)O.N

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pyruvate SCHEMBL27809991 1.00
Pyruvate SCHEMBL30036647 0.95
Pyruvate SCHEMBL300872 0.95
Pyruvate SCHEMBL1750 0.95
Pyruvate SCHEMBL13165964 0.95
Pyruvate SCHEMBL23829857 0.95
Pyruvate SCHEMBL29358755 0.95
Pyruvate SCHEMBL274319 0.95 TSHR (0.60)
Pyruvate SCHEMBL8710299 0.95
Pyruvate SCHEMBL8710301 0.95 TSHR (0.60)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 228 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114410702-B Method for preparing levodopa by recycling mother liquor 浙江永太手心医药科技有限公司 2024-09-20 CN claimed
CN-114920851-B Aβ1-42 antigen and use thereof for detecting Aβ1-42 concentration in Alzheimer's patient 福建亿彤生物科技有限公司 2024-05-31 CN claimed
CN-114989313-B P-tau181 epitope peptide and application thereof in Alzheimer disease detection 福建亿彤生物科技有限公司 2024-04-02 CN claimed
US-11905491-B2 Post CMP cleaning compositions ENTEGRIS, INC. (US) 2024-02-20 US claimed
US-11845917-B2 Compositions and methods for post-CMP cleaning of cobalt substrates ENTEGRIS, INC. (US) 2023-12-19 US claimed
CN-114836407-B Method for modifying polypeptide by chitinase 3-like protein 1 antigen and carrier protein 亿彤科技发展(福建)有限公司 2023-09-01 CN claimed
EP-4225882-A1 POST CMP CLEANING COMPOSITIONS Entegris, Inc. (US) 2023-08-16 EP claimed
CN-116457447-A POST chemical mechanical polishing (POST CMP) cleaning compositions 恩特格里斯公司 2023-07-18 CN claimed
CN-110791536-B Biosynthesis method of levodopa 南通大学 2023-01-17 CN claimed
CN-114989313-A P-tau181 epitope peptide and application thereof in Alzheimer disease detection 亿彤科技发展(福建)有限公司 2022-09-02 CN claimed
WO-2009020582-A1 METHOD FOR TREATING A PULMONARY DISEASE STATE IN MAMMALS BY UP OR DOWN REGULATING INDIGENOUS IN VIVO LEVELS OF INFLAMMATORY AGENTS IN MAMMALIAN CELLS CELLULAR SCIENCES, INC. (US) 2009-02-12 WO claimed
US-20090041738-A1 Method for treating a pulmonary disease state in mammals by up or down regulating indigenous in vivo levels of inflammatory agents in mammalian cells CELLULAR SCIENCES, INC. 2009-02-12 US claimed
EP-1855721-A1 METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES AND INJURIES CAUSED BY THE OVER-EXPRESSION OF PEROXYNITRITE North Cell Pharmaceutical, Inc. (US) 2007-11-21 EP claimed
EP-1627052-A4 PYRUVATE PRODUCING YEAST STRAIN STALEY MFG CO A E (US) 2007-07-04 EP claimed
WO-2006086643-A1 METHOD AND COMPOSITION FOR TREATING MAMMALIAN DISEASES AND INJURIES CAUSED BY THE OVER-EXPRESSION OF PEROXYNITRITE NORTH CELL PHARMACEUTICAL, INC. (US) 2006-08-17 WO claimed
EP-1627052-A2 PYRUVATE PRODUCING YEAST STRAIN A.E. STALEY MANUFACTURING COMPANY (US) 2006-02-22 EP claimed
US-20050244937-A1 Contacting a polypeptide with tryptophan or 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid to facilitate a conversion of tryptophan to indole-3-pyruvate, a conversion of 2-hydroxy 2-(indol-3-ylmethyl)-4-keto glutaric acid to 2-Hydroxy-2-(indol-3-ylmethyl)-4-aminoglutaric acid (monatin) CARGILL, INC. 2005-11-03 US claimed
US-20050197397-A1 Method and composition for treating mammalian diseases and injuries caused by the over-expression of peroxynitrite NORTH CELL PHARMACEUTICAL 2005-09-08 US claimed
US-20050059136-A1 Pyruvate producing yeast strain A.E. STALEY MANUFACTURING CO. 2005-03-17 US claimed
WO-2004099425-A2 PYRUVATE PRODUCING YEAST STRAIN A.E. STALEY MANUFACTURING CO. (US) 2004-11-18 WO claimed