Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 16/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 15/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5645476 | 0.91 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL5991307 | 0.84 | MRGPRX4 (0.33) | PTGS2PTGS1MRGPRX4RXRARXRB | |
| SCHEMBL5644337 | 0.79 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL6094295 | 0.72 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6093455 | 0.72 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL5645391 | 0.70 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL5646153 | 0.70 | PTGS2 (0.54) | PTGS2PTGS1 | |
| SCHEMBL6790596 | 0.66 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL31539107 | 0.65 | PTGS2 (0.55) | PTGS2PTGS1 | |
| SCHEMBL5647228 | 0.64 | PTGS2 (0.44) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615905-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | Pharmacia Corporation (US) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004087686-A2 | BENZOPYRAN COMPOUNDS USEFUL FOR TREATING INFLAMMATORY CONDITIONS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |