Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 14/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 14/20 | 0.75 |
| ▸ | MAPT | P10636 | 13/20 | 0.75 |
| ▸ | POLB | P06746 | 13/20 | 0.75 |
| ▸ | RECQL | P46063 | 12/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.75 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.75 |
| ▸ | LMNA | P02545 | 4/20 | 0.75 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 10/20 | 0.67 |
| ▸ | USP2 | O75604 | 7/20 | 0.67 |
| ▸ | APEX1 | P27695 | 5/20 | 0.67 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.67 |
| ▸ | ALPL | P05186 | 4/20 | 0.67 |
| ▸ | NSD2 | O96028 | 3/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.64 |
| ▸ | BLM | P54132 | 7/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8592041 | 0.87 | MAPT (0.66) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL14213566 | 0.83 | MEN1 (0.71) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL6886015 | 0.82 | MAPT (0.88) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL6885414 | 0.78 | MAPT (0.81) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL6885417 | 0.78 | MAPT (0.81) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL26485785 | 0.78 | MAPT (0.65) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL26458902 | 0.78 | MAPT (1.00) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL14680220 | 0.78 | MAPT (1.00) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL18598496 | 0.75 | MAPT (0.83) | MEN1KMT2AMAPTPOLBRECQL | |
| SCHEMBL1655144 | 0.74 | MEN1 (0.78) | MEN1KMT2AMAPTPOLBRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |