Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PGD | P52209 | 1/20 | 0.31 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8567184 | 1.00 | TSHR (0.35) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| Ammonia Solution, Strong SCHEMBL27515446 | 0.98 | TSHR (0.33) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL277198 | 0.82 | TSHR (0.36) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL11414967 | 0.82 | TSHR (0.36) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL8570869 | 0.81 | ACACB (0.35) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL28094878 | 0.80 | ALDH1A1 (0.35) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL9710095 | 0.78 | TSHR (0.33) | TSHRALDH1A1CYP2D6CYP2C19HIF1A | |
| SCHEMBL6195441 | 0.78 | CPT2 (0.40) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL15389946 | 0.78 | TSHR (0.33) | TSHRALDH1A1TP53CYP2D6CYP2C19 | |
| SCHEMBL17938010 | 0.78 | RNPEP (0.34) | TSHRALDH1A1CYP2D6CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524476-B2 | Bacterium producing a product of a reaction catalyzed by a protein having 2-oxoglutarate-dependent enzyme activity and a method for manufacturing the product | AJINOMOTO CO., INC. (JP) | 2013-09-03 | — | — | US | disclosed |
| US-8114651-B2 | Method for producing 4-hydroxy-L-isoleucine | AJINOMOTO CO., INC. (JP) | 2012-02-14 | — | — | US | disclosed |
| WO-2011021717-A2 | METHOD FOR PRODUCING HYDROXYLATED AMINO ACIDS | AJINOMOTO CO.,INC. (JP) | 2011-02-24 | — | — | WO | disclosed |
| US-20100330622-A1 | BACTERIUM PRODUCING A PRODUCT OF A REACTION CATALYZED BY A PROTEIN HAVING 2-OXOGLUTARATE-DEPENDENT ENZYME ACTIVITY AND A METHOD FOR MANUFACTURING THE PRODUCT | AJINOMOTO CO., INC. (JP) | 2010-12-30 | — | — | US | disclosed |