Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.71 |
| ▸ | PPARD | Q03181 | 18/20 | 0.71 |
| ▸ | PPARA | Q07869 | 16/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989804 | 0.91 | PPARG (0.76) | PPARGPPARDPPARA | |
| SCHEMBL6054868 | 0.88 | PPARG (0.78) | PPARGPPARDPPARA | |
| SCHEMBL6054863 | 0.88 | PPARG (0.78) | PPARGPPARDPPARA | |
| SCHEMBL5990739 | 0.86 | PPARG (0.67) | PPARGPPARDPPARA | |
| SCHEMBL5402959 | 0.85 | PPARG (0.80) | PPARGPPARDPPARA | |
| SCHEMBL5402967 | 0.85 | PPARG (0.80) | PPARGPPARDPPARA | |
| SCHEMBL5989779 | 0.85 | PPARG (0.67) | PPARGPPARDPPARA | |
| SCHEMBL5989089 | 0.84 | PPARG (0.77) | PPARGPPARDPPARA | |
| SCHEMBL5990033 | 0.84 | PPARG (0.57) | PPARGPPARDPPARAHPGD | |
| SCHEMBL5402182 | 0.83 | PPARG (1.00) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |