Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.57 |
| ▸ | PPARD | Q03181 | 14/20 | 0.57 |
| ▸ | PPARA | Q07869 | 12/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5989611 | 0.92 | PPARG (0.62) | PPARGPPARDPPARAFFAR4PTGDR2 | |
| Bicarbonate SCHEMBL6054872 | 0.88 | PPARG (0.58) | PPARGPPARDPPARAFFAR4PTGDR2 | |
| Bicarbonate SCHEMBL6054875 | 0.88 | PPARG (0.58) | PPARGPPARDPPARAFFAR4PTGDR2 | |
| SCHEMBL5992345 | 0.84 | PPARG (0.71) | PPARGPPARDPPARAHPGD | |
| SCHEMBL5989089 | 0.80 | PPARG (0.77) | PPARGPPARDPPARA | |
| SCHEMBL5990243 | 0.79 | PPARD (0.58) | PPARGPPARDPPARAPTGDR2 | |
| SCHEMBL5989905 | 0.78 | PPARG (0.64) | PPARGPPARDPPARA | |
| SCHEMBL5989901 | 0.78 | PPARG (0.64) | PPARGPPARDPPARA | |
| SCHEMBL5990495 | 0.76 | PPARG (0.65) | PPARGPPARDPPARA | |
| SCHEMBL5989779 | 0.75 | PPARG (0.67) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |