SCHEMBL5992610

SCHEMBL5992610

Cc1cn([C@@H]2O[C@]3(CO)CO[C@H]2[C@H]3O)c(=O)nc1N

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.37
ASGR1 P07306 4/20 0.33
ALB P02768 1/20 0.33
LMNA P02545 2/20 0.31
MTOR P42345 2/20 0.31
THRB P10828 1/20 0.31
MDM2 Q00987 1/20 0.31
NCOA1 Q15788 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
GMNN O75496 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
NFKB1 P19838 1/20 0.31
DNMT1 P26358 1/20 0.31
THPO P40225 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
BLM P54132 1/20 0.31
HBB P68871 1/20 0.31
PMP22 Q01453 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4313991 1.00 ADORA3 (0.37) ADORA3ASGR1ALBLMNAMTOR
SCHEMBL14929428 1.00 ADORA3 (0.37) ADORA3ASGR1ALBLMNAMTOR
SCHEMBL4313984 1.00 ADORA3 (0.37) ADORA3ASGR1ALBLMNAMTOR
SCHEMBL24429180 0.91 ALB (0.31) ADORA3ALB
SCHEMBL14946290 0.90 ALB (0.32) ALB
SCHEMBL18574253 0.89 ALB (0.32) ADORA3ALB
SCHEMBL21998922 0.89 ALB (0.32) ALB
SCHEMBL5996205 0.89 ALB (0.32) ALB
SCHEMBL23906488 0.89 ALB (0.34) ALB
SCHEMBL21999798 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7034133-B2 Locked Nucleoside Analogues is a biochemical conjugate of nucleotides; as an aptamer in specific binding of antibiotics, drugs, amino acids, peptides, enzymes, saccharides, polysaccharides; heat resistance EXIQON A/S (DK) 2006-04-25 US claimed