Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 7/20 | 0.80 |
| ▸ | KDM4D | Q6B0I6 | 3/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | THRB | P10828 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 2/20 | 0.62 |
| ▸ | BLM | P54132 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.59 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5995022 | 0.85 | KDM4D (1.00) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL20272250 | 0.83 | KDM4D (0.82) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL9613317 | 0.81 | KDM4D (0.82) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL9613328 | 0.80 | PTPN7 (1.00) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL20866496 | 0.80 | PTPN7 (0.77) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL14680156 | 0.79 | ALDH1A1 (0.69) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL9613294 | 0.76 | KDM4D (0.73) | PTPN7KDM4DKMT2AMEN1MAPT | |
| SCHEMBL30557433 | 0.75 | MAPT (0.81) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL3822948 | 0.75 | MAPT (0.81) | KMT2AMEN1MAPTALDH1A1HPGD | |
| SCHEMBL9613359 | 0.75 | PTPN7 (0.77) | PTPN7KDM4DKMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |