Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 4/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3920012 | 0.90 | MRGPRX4 (0.46) | MRGPRX4CYP11B1CYP11B2NSD2NSD3 | |
| SCHEMBL3918849 | 0.88 | MRGPRX4 (0.51) | MRGPRX4CYP11B1CYP11B2TP53GAA | |
| SCHEMBL3915224 | 0.86 | MRGPRX4 (0.52) | MRGPRX4CYP11B1CYP11B2TP53GAA | |
| SCHEMBL3915058 | 0.82 | CYP11B1 (0.51) | MRGPRX4CYP11B1CYP11B2TP53GAA | |
| SCHEMBL3919607 | 0.79 | CYP11B1 (0.44) | MRGPRX4CYP11B1CYP11B2NSD2NSD3 | |
| SCHEMBL11037750 | 0.77 | ALDH1A1 (0.50) | MRGPRX4CYP11B1CYP11B2TP53NSD2 | |
| SCHEMBL225912 | 0.77 | MRGPRX4 (0.48) | MRGPRX4CYP11B1CYP11B2NSD2NSD3 | |
| SCHEMBL27914171 | 0.75 | MAOB (0.51) | NSD2NSD3XDHALDH1A1HPGD | |
| SCHEMBL13223331 | 0.75 | CYP11B1 (0.51) | MRGPRX4CYP11B1CYP11B2NSD2NSD3 | |
| SCHEMBL6245912 | 0.73 | MRGPRX4 (0.52) | MRGPRX4CYP11B1CYP11B2NSD2NSD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1716110-A1 | ANDROGEN RECEPTOR MODULATORS | Warner-Lambert Company LLC (US) | 2006-11-02 | — | — | EP | claimed |
| WO-2005080320-A1 | ANDROGEN RECEPTOR MODULATORS | WARNER-LAMBERT COMPANY LLC (US) | 2005-09-01 | — | — | WO | claimed |