SCHEMBL5994658

SCHEMBL5994658

CCCCP(=O)(C(=O)c1c(C)cccc1C)C(=O)c1c(C)cc(C)cc1C

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
F2R P25116 1/20 0.39
ITGB1 P05556 1/20 0.38
ITGA4 P13612 1/20 0.38
TRPA1 O75762 1/20 0.36
TSHR P16473 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.34
POLB P06746 1/20 0.34
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2497195 0.92 HPGD (0.41) SMN1; SMN2HPGDKMT2AMEN1LMNA
SCHEMBL6467225 0.92 TSHR (0.41) SMN1; SMN2KMT2AMEN1F2RTSHR
SCHEMBL5995012 0.90 TSHR (0.38) SMN1; SMN2HPGDKMT2AMEN1LMNA
SCHEMBL5995028 0.89 MEN1 (0.40) SMN1; SMN2HPGDKMT2AMEN1LMNA
SCHEMBL2064034 0.88 ITGB1 (0.41) SMN1; SMN2HPGDKMT2AMEN1LMNA
SCHEMBL6470382 0.88 CETP (0.42) KMT2AMEN1F2RTSHRL3MBTL1
SCHEMBL5995713 0.87 CNR1 (0.37) SMN1; SMN2KMT2AMEN1F2RTSHR
SCHEMBL5995310 0.87 TAS1R3 (0.41) KMT2AMEN1F2RTSHRL3MBTL1
SCHEMBL444511 0.87 PPARA (0.42) SMN1; SMN2KMT2AMEN1ITGB1ITGA4
SCHEMBL6465547 0.86 CETP (0.44) KMT2AMEN1F2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 SMN1; SMN2 3940/4885HPGD 2368/4885KMT2A 1784/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 SMN1; SMN2 1663/4885HPGD 3137/4885KMT2A 761/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 SMN1; SMN2 4099/4885HPGD 3884/4885KMT2A 1577/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.