SCHEMBL5994729

SCHEMBL5994729

Cc1cc(C)c(C(=O)[P](=O)C(CC(C)CC(C)(C)C)c2ccccc2)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.33
KDM4E B2RXH2 1/20 0.33
NPSR1 Q6W5P4 2/20 0.32
ATM Q13315 1/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32
ALDH1A1 P00352 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
BRD4 O60885 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
HPGD P15428 1/20 0.30
MCOLN3 Q8TDD5 1/20 0.30
CACNA1G O43497 1/20 0.30
CACNA2D1 P54289 1/20 0.30
CACNA1B Q00975 1/20 0.30
CACNB1 Q02641 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995143 0.81 L3MBTL1 (0.35) L3MBTL1KDM4ENPSR1HPGDMCOLN3
SCHEMBL5996191 0.81 CA12 (0.38) KDM4EALDH1A1MEN1KMT2ASMN1; SMN2
SCHEMBL5997935 0.78 KDM4E (0.33) LMNAL3MBTL1KDM4ENPSR1MEN1
SCHEMBL5996270 0.76 KDM4E (0.32) L3MBTL1KDM4E
SCHEMBL27561222 0.76 POLB (0.39) KDM4ESLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL27498752 0.76 NPSR1 (0.39) LMNAL3MBTL1NPSR1SLC6A2SLC6A4
SCHEMBL6818017 0.74 BCL2L1 (0.31) L3MBTL1KDM4E
SCHEMBL27500591 0.74 NPSR1 (0.37) LMNAL3MBTL1NPSR1ATMSLC6A2
SCHEMBL5994345 0.74 ITGB1 (0.30)
SCHEMBL17818680 0.73 L3MBTL1 (0.36) LMNAL3MBTL1KDM4ENPSR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7026017-B2 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-04-11 US disclosed
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-6737549-B2 PHOTOINITIATORS FOR ACRYLATE COATINGS CIBA SPECIALTY CHEMICALS CORPORATION 2004-05-18 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation WOLF JEAN-PIERRE (CH) 2003-07-10 US disclosed
US-20020026049-A1 Photoinitiators for acrylate coatings CIBA SPECIALTY CHEMICALS CORP. 2002-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 LMNA 763/4885L3MBTL1 1852/4885KDM4E 3308/4885
US-20030130370-A1 Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation SMARCC1, ARPC5L, DHCR24 LMNA 975/4885L3MBTL1 1879/4885KDM4E 662/4885
US-20020026049-A1 Photoinitiators for acrylate coatings DHCR24, NR5A1, NR2C2 LMNA 848/4885L3MBTL1 2570/4885KDM4E 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.