Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCK | P27707 | 5/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | EP300 | Q09472 | 4/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL598439 | 0.93 | ALB (0.36) | DCKALBEP300 | |
| SCHEMBL597635 | 0.91 | ALB (0.35) | ALBEP300 | |
| SCHEMBL598272 | 0.91 | DCK (0.35) | DCKALBEP300 | |
| SCHEMBL599040 | 0.90 | DCK (0.42) | DCKALBCDK2SMN1; SMN2 | |
| SCHEMBL599086 | 0.90 | EP300 (0.37) | ALBEP300 | |
| SCHEMBL598689 | 0.90 | DCK (0.39) | DCKALBEP300CDK2SMN1; SMN2 | |
| SCHEMBL599309 | 0.89 | ALB (0.33) | ALBEP300 | |
| SCHEMBL598541 | 0.84 | DCK (0.37) | DCKALBMAPTSMN1; SMN2 | |
| SCHEMBL597780 | 0.83 | ALB (0.39) | ALBEP300 | |
| SCHEMBL599573 | 0.80 | ALB (0.36) | ALBEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8114997-B2 | N4-acylcytosine nucleosides for treatment of viral infections | PHARMASSET, INC. (US) | 2012-02-14 | — | — | US | disclosed |