Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.69 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 13/20 | 0.49 |
| ▸ | THRA | P10827 | 4/20 | 0.49 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6342801 | 0.86 | MEN1 (0.71) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5562109 | 0.85 | MEN1 (0.69) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL10419955 | 0.83 | MEN1 (0.64) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL10394519 | 0.83 | MEN1 (0.64) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5567070 | 0.82 | MEN1 (0.60) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL6345637 | 0.82 | MEN1 (0.65) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5566905 | 0.82 | MEN1 (0.65) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL9823772 | 0.82 | MEN1 (0.65) | MEN1NR1I2KMT2ATHRBTHRA | |
| Diclazuril SCHEMBL126138 | 0.82 | MEN1 (1.00) | MEN1NR1I2KMT2ATHRBTHRA | |
| SCHEMBL5566019 | 0.81 | MEN1 (0.64) | MEN1NR1I2KMT2ATHRBTHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012065139-A2 | ENTPD5 INHIBITORS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2012-05-18 | — | — | WO | disclosed |