SCHEMBL599510

SCHEMBL599510

Cc1c(C)c(C=O)c(C)c(C)c1C=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IGF1R P08069 1/20 0.34
SRC P12931 1/20 0.34
AXL P30530 1/20 0.34
PTK2 Q05397 1/20 0.34
AURKB Q96GD4 1/20 0.34
ALK Q9UM73 1/20 0.34
MAOB P27338 1/20 0.33
CYP2A6 P11509 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 4/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
TSHR P16473 1/20 0.30
CYP3A4 P08684 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2925279 0.96 L3MBTL1 (0.36) IGF1RSRCAXLPTK2AURKB
SCHEMBL3129826 0.93 L3MBTL1 (0.35) IGF1RSRCAXLPTK2AURKB
SCHEMBL12080026 0.92 IGF1R (0.34) IGF1RSRCAXLPTK2AURKB
SCHEMBL599509 0.88 L3MBTL1 (0.36) IGF1RSRCAXLPTK2AURKB
SCHEMBL607624 0.88 IGF1R (0.33) IGF1RSRCAXLPTK2AURKB
SCHEMBL605256 0.85 L3MBTL1 (0.35) IGF1RSRCAXLPTK2AURKB
SCHEMBL11505405 0.84
SCHEMBL3271864 0.84 IGF1R (0.42) IGF1RSRCAXLPTK2AURKB
SCHEMBL751512 0.82 KDM4E (0.34) MAOBMEN1KMT2AMAPTKDM4E
SCHEMBL14164102 0.80 IGF1R (0.39) IGF1RSRCAXLPTK2AURKB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 251 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1276027-C Composite polyamide/clay material and its prepn and use CHINESE ACAD INST CHEMISTRY (CN) 2006-09-20 CN claimed
CN-1609143-A Composite polyamide/clay material and its prepn and use CHINESE ACAD INST CHEMISTRY (CN) 2005-04-27 CN claimed
EP-1386603-A1 Use of diamines having at least one quaternised group and dialdehydes for dyeing keratin fibres L'OREAL (FR) 2004-02-04 EP claimed
EP-4389263-A1 SUBSTITUTED TRIANGLAMINE AND USES THEREOF Centre national de la recherche scientifique (FR) 2024-06-26 EP disclosed
CN-117510476-A Plinabulin derivative, preparation method and application thereof 中国科学院长春应用化学研究所 2024-02-06 CN disclosed
WO-2024022375-A1 PLINABULIN DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国科学院长春应用化学研究所 2024-02-01 WO disclosed
CN-110229333-B Synthetic method of polyimide 湘潭大学 2022-02-15 CN disclosed
CN-107848926-B Novolac type phenolic hydroxyl group-containing resin and resist film DIC株式会社 2021-04-20 CN disclosed
CN-108368214-B Novolac resin and resist film DIC株式会社 2021-03-23 CN disclosed
EP-1890992-B1 AN ENRICHMENT PROCESS USING COMPOUNDS USEFUL IN A POLYESTER PROCESS GRUPO PETROTEMEX SA DE CV (MX) 2019-10-23 EP disclosed
WO-2019198550-A1 CYANIC ACID ESTER COMPOUND AND METHOD FOR PRODUCING SAME, RESIN COMPOSITION, CURED ARTICLE, SINGLE-LAYER RESIN SHEET, LAMINATED RESIN SHEET, PREPREG, METAL-FOIL-CLAD LAMINATED PLATE, PRINTED WIRING BOARD, SEALING MATERIAL, FIBER-REINFORCED COMPOSITE MATERIAL, AND ADHESIVE AGENT 三菱瓦斯化学株式会社 2019-10-17 WO disclosed
US-5068292-A Reaction of monomers to form rigid polymer rods followed by reaction of matrix polymers in situ GENCORP INC. (US) 1991-11-26 US disclosed
EP-0408166-A2 Composite polymeric materials GENCORP INC. (US) 1991-01-16 EP disclosed
US-4950732-A RADIATION RESISTANCE EASTMAN KODAK COMPANY 1990-08-21 US disclosed
US-4883844-A FROM AROMATIC ALDEHYDE AND SUBSTITUTED PYRIDINE THE DOW CHEMICAL COMPANY (US) 1989-11-28 US disclosed
EP-0272692-A2 Condensation copolymers containing bis-methine moieties and products therefrom EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1988-06-29 EP disclosed
US-4726942-A SUNSCREEN AGENTS L'OREAL (FR) 1988-02-23 US disclosed
US-4663088-A COSMETIC SUNSCREENS L'OREAL (FR) 1987-05-05 US disclosed
US-4654434-A SUN FILTERS L'OREAL (FR) 1987-03-31 US disclosed
US-4585597-A 3-benzylidene-camphors, process for their preparation and their use in protection against UV rays L'OREAL (FR) 1986-04-29 US disclosed