Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963750 | 1.00 | HTR3A (0.46) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A | |
| SCHEMBL1965988 | 0.93 | HTR3A (0.46) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A | |
| SCHEMBL1965990 | 0.93 | HTR3A (0.46) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A | |
| SCHEMBL1964594 | 0.92 | HTR3A (0.44) | HTR3ACHRNA7 | |
| SCHEMBL491877 | 0.90 | HTR3A (0.46) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A | |
| SCHEMBL492414 | 0.89 | HTR3A (0.45) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A | |
| SCHEMBL4638667 | 0.87 | HTR3A (0.44) | HTR3ACHRNA7 | |
| SCHEMBL491969 | 0.87 | HTR3A (0.44) | HTR3ACHRNA7 | |
| SCHEMBL1963562 | 0.86 | CHRNA7 (0.44) | HTR3ACHRNA7MEN1KMT2AATM | |
| SCHEMBL2790861 | 0.85 | HTR3A (0.44) | HTR3ACHRNA7CYP1A2CYP2C19RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1735306-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | Memory Pharmaceuticals Corporation (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005092890-A2 | INDAZOLES, BENZOTHIAZOLES, BENZOISOTHIAZOLES, BENZISOXAZOLES, AND PREPARATION AND USES THEREOF | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-10-06 | — | — | WO | disclosed |