Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.48 |
| ▸ | CCNC | P24863 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | SRC | P12931 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7347385 | 0.99 | CYP1A2 (0.48) | CYP1A2CYP2C19NCEH1CCNCCDK8 | |
| SCHEMBL5997308 | 0.81 | CYP1A2 (0.53) | CYP1A2CYP2C19NCEH1CCNCCDK8 | |
| SCHEMBL6615856 | 0.81 | CDYL (0.60) | CYP1A2CYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL30498970 | 0.81 | CDYL (0.60) | CYP1A2CYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL17537545 | 0.81 | ALDH1A1 (0.54) | CYP1A2CYP2C19CCNCCDK8KDM4E | |
| SCHEMBL6773955 | 0.79 | EGFR (0.49) | CYP1A2CYP2C19NCEH1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL27506548 | 0.78 | EGFR (0.48) | CYP1A2CYP2C19NCEH1KDM4EALDH1A1 | |
| SCHEMBL7832666 | 0.78 | CYP4F2 (0.46) | CYP1A2CYP2C19NCEH1KDM4EALDH1A1 | |
| SCHEMBL28309323 | 0.76 | ALDH1A1 (0.57) | CYP1A2CYP2C19KDM4EALDH1A1MAPT | |
| SCHEMBL20834863 | 0.75 | CYP4F2 (0.44) | KDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7087759-B2 | for controlling weight; pyrrolidine or piperidine compounds | THE PROCTER & GAMBLE COMPANY (US) | 2006-08-08 | — | — | US | disclosed |
| US-20060106059-A1 | Melanocortin receptor ligands | MAZUR WIESLAW A | 2006-05-18 | — | — | US | disclosed |
| US-6911447-B2 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY (US) | 2005-06-28 | — | — | US | disclosed |
| US-20040224985-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2004-11-11 | — | — | US | disclosed |
| US-20030109556-A1 | Melanocortin receptor ligands | THE PROCTER & GAMBLE COMPANY | 2003-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109556-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | CYP1A2 1953/4885CYP2C19 796/4885NCEH1 2326/4885 |
| US-20060106059-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | CYP1A2 2334/4885CYP2C19 1037/4885NCEH1 1832/4885 |
| US-20040224985-A1 | Melanocortin receptor ligands | MC3R, MC4R, MC1R | CYP1A2 1953/4885CYP2C19 796/4885NCEH1 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.