Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA4 | P22748 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9506373 | 0.98 | CA1 (0.53) | CA1CA2CA4CA5ACA5B | |
| Toluene SCHEMBL28660791 | 0.84 | ALDH1A1 (0.52) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL9102180 | 0.79 | CA1 (0.53) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL10987455 | 0.79 | CA1 (0.58) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL28674576 | 0.79 | CA1 (0.53) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL14012564 | 0.79 | CA1 (0.53) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11721552 | 0.77 | CNR2 (0.41) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL11584394 | 0.76 | — | — | |
| SCHEMBL254763 | 0.76 | CA1 (0.46) | CA1CA2CA4CA5ACA5B | |
| SCHEMBL10220180 | 0.76 | CA1 (0.50) | CA1CA2CA4CA5ACA5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118638076-A | Preparation method of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 湖南化工研究院有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118084821-A | Preparation method of tebuthiuron | 湖南化工研究院有限公司 | 2024-05-28 | — | — | CN | claimed |
| CN-117986169-A | Synthesis method of intermediate 4-methylaminothiourea of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 宁夏常晟药业有限公司 | 2024-05-07 | — | — | CN | claimed |
| CN-117603160-A | Synthesis method of high-purity tebuthiuron | 山东华阳农药化工集团有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-218854256-U | Variable pressure type synthetic reaction system of tebuthiuron | 江苏常隆农化有限公司 | 2023-04-14 | — | — | CN | claimed |
| CN-113620905-A | Industrial production method of tebuthiuron technical | 江苏快达农化股份有限公司 | 2021-11-09 | — | — | CN | claimed |
| CN-110372634-B | Method for synthesizing 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 宁夏常晟药业有限公司 | 2021-03-19 | — | — | CN | claimed |
| CN-110372634-A | A method of synthesis 2- methylamino -5- tert-butyl -1,3,4- thiadiazoles | 宁夏晟丰元化工有限公司 | 2019-10-25 | — | — | CN | claimed |
| CN-109251188-A | A kind of preparation method of 2- methylamino -5- tert-butyl -1,3,4- thiadiazoles | 河北工业大学 | 2019-01-22 | — | — | CN | claimed |
| CN-105524017-A | Preparation method of 2-methylamino-5-t-butyl-1,3,4-thiadiazole | JIANGSU HANLIAN BIOTECHNOLOGY CO LTD | 2016-04-27 | — | — | CN | claimed |
| US-4987233-A | Process for preparing herbicidal ureas and insecticidal carbamates and carbamate derivatives | ELI LILLY AND COMPANY (US) | 1991-01-22 | — | — | US | claimed |
| US-4283543-A | Process for preparing the compound 5-t-butyl-2-methylamino-1,3,4-triadiazole | MORTON-NORWICH PRODUCTS, INC. (US) | 1981-08-11 | — | — | US | claimed |
| CN-118638076-B | Preparation method of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 湖南化工研究院有限公司 | 2026-04-28 | — | — | CN | disclosed |
| CN-118638076-B | Preparation method of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 湖南化工研究院有限公司 | 2026-04-28 | — | — | CN | disclosed |
| CN-121758393-A | Synthesis method of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 宁夏常晟药业有限公司 | 2026-03-31 | — | — | CN | disclosed |
| CN-121758393-A | Synthesis method of 2-methylamino-5-tert-butyl-1, 3, 4-thiadiazole | 宁夏常晟药业有限公司 | 2026-03-31 | — | — | CN | disclosed |
| US-4283543-A | Process for preparing the compound 5-t-butyl-2-methylamino-1,3,4-triadiazole | MORTON-NORWICH PRODUCTS, INC. (US) | 1981-08-11 | — | — | US | disclosed |
| US-4237066-A | Preparation of lower alkyl thiosemicarbazides | MOBAY CHEMICAL CORPORATION (US) | 1980-12-02 | — | — | US | disclosed |
| US-4132736-A | Preparation of 4-alkylthiosemicarbazides | BAYER AKTIENGESELLSCHAFT (DE) | 1979-01-02 | — | — | US | disclosed |
| US-4086077-A | 1,3-DIMETHYL-1-(5-TERT-BUTYL-1,3,4-THIADIAZOL-2-YL) UREA, HERBICIDES | GULF RESEARCH & DEVELOPMENT COMPANY (US) | 1978-04-25 | — | — | US | disclosed |