Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.46 |
| ▸ | PIN4 | Q9Y237 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997717 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1PIN1PIN4L3MBTL1 | |
| SCHEMBL5997034 | 1.00 | KMT2A (0.49) | KMT2AALDH1A1PIN1PIN4L3MBTL1 | |
| SCHEMBL5998685 | 0.88 | ALDH1A1 (0.44) | KMT2AALDH1A1PIN1PIN4MEN1 | |
| SCHEMBL5997722 | 0.88 | ALDH1A1 (0.44) | KMT2AALDH1A1PIN1PIN4MEN1 | |
| SCHEMBL5997726 | 0.88 | ALDH1A1 (0.44) | KMT2AALDH1A1PIN1PIN4MEN1 | |
| SCHEMBL29777966 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL5998953 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL7266878 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL29740352 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPK1MAPTRAB9A | |
| SCHEMBL5998957 | 0.87 | ALDH1A1 (0.50) | KMT2AALDH1A1MAPK1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | claimed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | claimed |
| US-7094908-B2 | Reduction of carbonyl compounds using the carbonyl reductase of Kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-22 | — | — | US | disclosed |
| US-7091016-B2 | Carbonyl reductase of Kluyveromyces marxianus and its isolation and purification method | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2006-08-15 | — | — | US | disclosed |
| US-20030170844-A1 | Carbonyl reductase of kluyveromyces marxianus and its isolation and purification method | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-09-11 | — | — | US | disclosed |
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139464-A1 | Reduction of carbonyl compounds using the carbonyl reductase of kluyveromyces marxianus | CBR1, CBR3, DCXR | KMT2A 1280/4885ALDH1A1 216/4885PIN1 1143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.