Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 4/20 | 0.47 |
| ▸ | SRC | P12931 | 8/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 7/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 4/20 | 0.43 |
| ▸ | CDK4 | P11802 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.39 |
| ▸ | TEK | Q02763 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5997334 | 0.83 | KDR (0.48) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL5998026 | 0.82 | LCK (0.57) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL5999296 | 0.82 | KIT (0.54) | ABL1SRCLCKMAPK14KDR | |
| SCHEMBL5996905 | 0.82 | LCK (0.49) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL2496233 | 0.82 | MEN1 (0.49) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL5996827 | 0.81 | SRC (0.54) | ABL1SRCPDGFRBKDREPHX2 | |
| SCHEMBL5995458 | 0.81 | SRC (0.56) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL2498530 | 0.81 | CSF1R (0.51) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL12212561 | 0.80 | SRC (0.46) | ABL1SRCPDGFRBLCKMAPK14 | |
| SCHEMBL5995422 | 0.80 | ABL1 (0.53) | ABL1SRCPDGFRBLCKMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | TARGEGEN, INC. (US) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247250-A1 | Pyrimidine inhibitors of kinases | DTYMK, SRC, DCK | ABL1 12/4885SRC 2/4885PDGFRB 97/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.