Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27506648 | 0.98 | FASN (0.38) | FASNLMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL5997848 | 0.88 | CYP2D6 (0.51) | LMNAHTR1AADRA2ACYP2D6ADRA2C | |
| SCHEMBL27507081 | 0.86 | CYP2D6 (0.50) | LMNAHTR1AADRA2ACYP2D6ADRA2C | |
| SCHEMBL27506650 | 0.81 | CA12 (0.47) | SMN1; SMN2POLB | |
| SCHEMBL5995800 | 0.80 | ALDH1A1 (0.40) | LMNAALDH1A1SMN1; SMN2POLBGAA | |
| SCHEMBL5997300 | 0.80 | FASN (0.43) | FASNLMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL5997305 | 0.78 | SMN1; SMN2 (0.42) | CTNNB1WNT3AALDH1A1SMN1; SMN2ACHE | |
| SCHEMBL5995429 | 0.78 | ALDH1A1 (0.36) | FASNALDH1A1 | |
| SCHEMBL12123732 | 0.78 | ALDH1A1 (0.52) | FASNLMNAHTR1AADRA2ACYP2D6 | |
| SCHEMBL5996208 | 0.77 | MAPT (0.37) | LMNACTNNB1WNT3AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109250-B2 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. (US) | 2006-09-19 | — | — | US | disclosed |
| US-7026017-B2 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2006-04-11 | — | — | US | disclosed |
| US-6969733-B2 | Photoinitiators | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2005-11-29 | — | — | US | disclosed |
| CN-1589276-A | Multimer of acylphosphines and their derivatives | CIBA SC HOLDING AG (CH) | 2005-03-02 | — | — | CN | disclosed |
| US-20050004247-A1 | Multimer forms of acylphosphines and their derivatives | CIBA SPECIALTY CHEMICALS CORP. | 2005-01-06 | — | — | US | disclosed |
| EP-1446410-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | Ciba SC Holding AG (CH) | 2004-08-18 | — | — | EP | disclosed |
| US-6737549-B2 | PHOTOINITIATORS FOR ACRYLATE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-05-18 | — | — | US | disclosed |
| US-20030139485-A1 | Photoinitiators | WOLF JEAN-PIERRE (CH) | 2003-07-24 | — | — | US | disclosed |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | WOLF JEAN-PIERRE (CH) | 2003-07-10 | — | — | US | disclosed |
| WO-2003044030-A1 | MULTIMER FORMS OF ACYLPHOSPHINES AND THEIR DERIVATIVES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2003-05-30 | — | — | WO | disclosed |
| US-20020026049-A1 | Photoinitiators for acrylate coatings | CIBA SPECIALTY CHEMICALS CORP. | 2002-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139485-A1 | Photoinitiators | DHCR24, NR1I3, CBR1 | FASN 1351/4885LMNA 763/4885HTR1A 732/4885 |
| US-20030130370-A1 | Photoinitiators for acrylic esters; reacting an acyl halide with a metal benzoyl phosphine; cable coatings, screen printing stencils, resist materials, colour filters, electrical encapsulation | SMARCC1, ARPC5L, DHCR24 | FASN 2990/4885LMNA 975/4885HTR1A 1932/4885 |
| US-20020026049-A1 | Photoinitiators for acrylate coatings | DHCR24, NR5A1, NR2C2 | FASN 2546/4885LMNA 848/4885HTR1A 169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.