SCHEMBL5998102

SCHEMBL5998102

CC(C)(Cc1cccc(CC(=O)NCc2ccc(Cl)cc2O)c1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1

nearest known ligand 0.90

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 20/20 0.90
CHRM3 P20309 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2456589 1.00 ADRB2 (0.90) ADRB2CHRM3
SCHEMBL2456584 1.00 ADRB2 (0.90) ADRB2CHRM3
SCHEMBL5041898 0.95 ADRB2 (0.89) ADRB2CHRM3
SCHEMBL5041896 0.95 ADRB2 (0.89) ADRB2CHRM3
SCHEMBL12305711 0.95 ADRB2 (1.00) ADRB2CHRM3
SCHEMBL2452299 0.92 ADRB2 (0.84) ADRB2CHRM3
SCHEMBL2452298 0.92 ADRB2 (0.84) ADRB2CHRM3
SCHEMBL5034540 0.91 ADRB2 (0.88) ADRB2CHRM3
SCHEMBL5034534 0.91 ADRB2 (0.88) ADRB2CHRM3
SCHEMBL5037702 0.91 ADRB2 (0.85) ADRB2CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2005080313-A9 SULFONAMIDE DERIVATIVES FOR THE TREATMENT OF DISEASES PFIZER LTD (GB) 2006-08-31 WO claimed