Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A2 | O95436 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAP3K7 | O43318 | 2/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 2/20 | 0.41 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.41 |
| ▸ | BRAF | P15056 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | GLS | O94925 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19596297 | 0.94 | SLC34A2 (0.50) | SLC34A2CHRM3ACKR3KDM4EMAP3K7 | |
| SCHEMBL46663 | 0.93 | MAP3K7 (0.47) | SLC34A2CHRM3ACKR3KCNH2CACNA1I | |
| SCHEMBL46724 | 0.92 | SLC34A2 (0.46) | SLC34A2CHRM3ACKR3KCNH2CACNA1I | |
| SCHEMBL10274674 | 0.91 | SLC34A2 (0.46) | SLC34A2CHRM3ACKR3DRD4 | |
| SCHEMBL46748 | 0.91 | CHRM3 (0.58) | SLC34A2CHRM3MAP3K7IRAK1IRAK4 | |
| SCHEMBL15420846 | 0.89 | SLC34A2 (0.48) | SLC34A2CHRM3KDM4EMAP3K7IRAK1 | |
| SCHEMBL46515 | 0.89 | SLC34A2 (0.51) | SLC34A2CHRM3KDM4EBRAFRAF1 | |
| SCHEMBL46985 | 0.89 | SLC34A2 (0.48) | SLC34A2CHRM3MAP3K7IRAK1IRAK4 | |
| SCHEMBL46725 | 0.89 | CHRM3 (0.56) | SLC34A2CHRM3MAP3K7IRAK1IRAK4 | |
| SCHEMBL46468 | 0.89 | CCR2 (0.48) | SLC34A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |