Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.37 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | CALML3 | P27482 | 1/20 | 0.33 |
| ▸ | SDHA | P31040 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5998076 | 0.96 | MAOA (0.39) | MAOAOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL5999433 | 0.88 | MAOA (0.38) | MAOACHRNB4CHRNA3OPRM1OPRK1 | |
| SCHEMBL5999423 | 0.88 | MAOA (0.38) | MAOACHRNB4CHRNA3OPRM1OPRK1 | |
| SCHEMBL5998696 | 0.88 | MAOA (0.50) | MAOACHRNB4CHRNA3OPRM1OPRK1 | |
| SCHEMBL5536716 | 0.88 | MAOA (0.50) | MAOACHRNB4CHRNA3OPRM1OPRK1 | |
| SCHEMBL5999489 | 0.84 | F10 (0.41) | MAOAMAOBF10TSHRMAPK1 | |
| SCHEMBL5503079 | 0.84 | MAOA (0.39) | MAOAMAOBF10LMNAPTGS1 | |
| SCHEMBL5999673 | 0.83 | MAOA (0.52) | MAOAOPRM1OPRK1OPRL1MAOB | |
| SCHEMBL5505548 | 0.82 | MAOA (0.38) | MAOAMAOBTSHRMAPK1LMNA | |
| SCHEMBL5505545 | 0.82 | MAOA (0.38) | MAOAMAOBTSHRMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060030609-A1 | Oxazolidinones containing oxindoles as antibacterial agents | LUEHR GARY W | 2006-02-09 | — | — | US | claimed |
| US-20060030609-A1 | Oxazolidinones containing oxindoles as antibacterial agents | LUEHR GARY W | 2006-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060030609-A1 | Oxazolidinones containing oxindoles as antibacterial agents | OXA1L, OXSR1, OXER1 | MAOA 766/4885CHRNB4 4764/4885CHRNA3 4548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.