SCHEMBL599875

SCHEMBL599875

CC(C(=O)O)c1ccsc1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.51
PTGS2 P35354 10/20 0.47
PTGS1 P23219 8/20 0.44
CYP2C9 P11712 4/20 0.44
LMNA P02545 4/20 0.44
CXCR1 P25024 4/20 0.44
CXCR2 P25025 4/20 0.44
AKR1C3 P42330 2/20 0.44
SLC22A6 Q4U2R8 2/20 0.44
CXCL8 P10145 2/20 0.44
PMP22 Q01453 2/20 0.44
ALB P02768 1/20 0.44
ESR1 P03372 1/20 0.44
RARB P10826 1/20 0.44
ADRB3 P13945 1/20 0.44
NFKB1 P19838 1/20 0.44
HTR2A P28223 1/20 0.44
NR1I3 Q14994 1/20 0.44
TSHR P16473 1/20 0.44
AKR1C2 P52895 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15675289 1.00 ALOX5 (0.51) ALOX5PTGS2PTGS1CYP2C9LMNA
Hydrochloric Acid SCHEMBL9402230 0.98 ALOX5 (0.50) ALOX5PTGS2PTGS1CYP2C9LMNA
SCHEMBL15695573 0.88 ALOX5 (0.51) ALOX5PTGS2PTGS1CYP2C9LMNA
SCHEMBL8910483 0.87 ALOX5 (0.42) ALOX5PTGS2PTGS1CYP2C9LMNA
SCHEMBL8716724 0.85 ALOX5 (0.53) ALOX5PTGS2PTGS1LCKFYN
SCHEMBL8352449 0.82 ALOX5 (0.50) ALOX5PTGS2PTGS1ALDH1A1LCK
SCHEMBL2656314 0.82 ALOX5 (0.59) ALOX5PTGS2PTGS1LCKFYN
SCHEMBL10968029 0.82 ALOX5 (0.50) ALOX5PTGS2PTGS1CYP2C9HPGD
Hydrochloric Acid SCHEMBL5347344 0.80 ALOX5 (0.57) ALOX5PTGS2PTGS1LCKFYN
SCHEMBL5511566 0.80 ALOX5 (0.49) ALOX5PTGS2PTGS1LMNAAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116076620-A Application of polyphenol lettuce in animal feed 浙江迦美善植物科技有限公司 2023-05-09 CN claimed
CN-110698456-B Synthesis method of 2, 3-dihydrothiochromen-4-one and derivatives thereof 重庆医药高等专科学校 2021-05-14 CN claimed
CN-103145692-B Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone YANCHENG INST TECHNOLOGY 2014-07-16 CN claimed
CN-103145692-A Preparation method of 4, 5-dihydro-6H-cyclopenta[b]thiophene-6-ketone YANCHENG INST TECHNOLOGY 2013-06-12 CN claimed
WO-2009055631-A1 CALCILYTIC COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2009-04-30 WO claimed
US-4690945-A ANTIINFLAMMATORY AGENTS; ANALGESICS LABORATORIOS MADAUS CERAFARM, S.A. (ES) 1987-09-01 US claimed
EP-4249470-B1 METHOD FOR PREPARING ALPHA-AMINO ACIDS PHILIPPS UNIV MARBURG (DE) 2024-11-13 EP disclosed
US-12128458-B1 Electrostatically-assisted two-step conductive polymer applique (CPA) paint removal process THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2024-10-29 US disclosed
EP-4332089-A1 METHOD FOR PREPARING AMINO ACIDS PHILIPPS-UNIVERSITÄT MARBURG (DE) 2024-03-06 EP disclosed
US-11819833-B2 Conducting polymer and carbon nitride based nanocomposite photocatalyst for degradation of aqueous organic pollutants Najran University (SA) 2023-11-21 US disclosed
US-20230330644-A1 CONDUCTING POLYMER AND CARBON NITRIDE BASED NANOCOMPOSITE PHOTOCATALYST FOR DEGRADATION OF AQUEOUS ORGANIC POLLUTANTS Najran University (SA) 2023-10-19 US disclosed
EP-4249470-A1 METHOD FOR PREPARING ALPHA-AMINO ACIDS PHILIPPS-UNIVERSITÄT MARBURG (DE) 2023-09-27 EP disclosed
US-11713397-B1 Composition for forming corrosion resistant composite coating KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-08-01 US disclosed
US-4845281-A Method of preparing ketoprofen BLASCHIM, S.P.A. (IT) 1989-07-04 US disclosed
EP-0309009-A1 Process for preparing ketoprofen Nobel Chemicals AB (SE) 1989-03-29 EP disclosed
US-4690945-A ANTIINFLAMMATORY AGENTS; ANALGESICS LABORATORIOS MADAUS CERAFARM, S.A. (ES) 1987-09-01 US disclosed
US-4690945-A ANTIINFLAMMATORY AGENTS; ANALGESICS LABORATORIOS MADAUS CERAFARM, S.A. (ES) 1987-09-01 US disclosed
EP-0002965-B1 A PROCESS FOR RECOVERING ACID CHLORIDES STAUFFER CHEMICAL COMPANY (US) 1981-03-11 EP disclosed
US-4204916-A Process for recovering acid chlorides by distillation STAUFFER CHEMICAL COMPANY (US) 1980-05-27 US disclosed
EP-0002965-A1 A process for recovering acid chlorides STAUFFER CHEMICAL COMPANY (US) 1979-07-11 EP disclosed