Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.64 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | CASP6 | P55212 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013650 | 1.00 | ADRB2 (0.64) | ADRB2CASP3CASP6 | |
| SCHEMBL4013647 | 1.00 | ADRB2 (0.64) | ADRB2CASP3CASP6 | |
| SCHEMBL4258495 | 0.95 | ADRB2 (0.71) | ADRB2 | |
| SCHEMBL4258497 | 0.95 | ADRB2 (0.71) | ADRB2 | |
| SCHEMBL4010820 | 0.94 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL4010825 | 0.94 | ADRB2 (0.61) | ADRB2 | |
| SCHEMBL4261097 | 0.93 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL4261104 | 0.93 | ADRB2 (0.60) | ADRB2 | |
| SCHEMBL5999190 | 0.92 | ADRB2 (0.59) | ADRB2 | |
| SCHEMBL4260747 | 0.92 | ADRB2 (0.62) | ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1624868-A1 | \"(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)- PROPYL!PHENYL DERIVATIVES AS BETA2 AGONISTS | Pfizer Limited (GB) | 2006-02-15 | — | — | EP | disclosed |
| WO-2004100950-A1 | ‘(2-HYDROXY-2-(4-HYDROXY-3-HYDOXYMETHYLPHENYL)-ETHYLAMINO)-PROPYL!PHENYL DERIVATIVES AS BETA2 AGONISTS | PFIZER LIMITED (GB) | 2004-11-25 | — | — | WO | disclosed |