Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 20/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46748 | 0.90 | CHRM3 (0.58) | CHRM3 | |
| SCHEMBL46725 | 0.88 | CHRM3 (0.56) | CHRM3 | |
| SCHEMBL19596297 | 0.84 | SLC34A2 (0.50) | CHRM3 | |
| SCHEMBL16355250 | 0.83 | SLC34A2 (0.51) | — | |
| SCHEMBL19579973 | 0.83 | SLC34A2 (0.53) | — | |
| SCHEMBL40118 | 0.83 | CHRM3 (0.43) | CHRM3 | |
| SCHEMBL15420846 | 0.81 | SLC34A2 (0.48) | CHRM3 | |
| SCHEMBL19595921 | 0.81 | HPGDS (0.45) | CHRM3 | |
| SCHEMBL46455 | 0.81 | CHRM3 (0.37) | CHRM3 | |
| SCHEMBL46985 | 0.81 | SLC34A2 (0.48) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054110-A2 | COMPOUNDS AND METHODS FOR INHIBITING PHOSPHATE TRANSPORT | ARDELYX, INC. (US) | 2012-04-26 | — | — | WO | disclosed |