Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 10/20 | 0.62 |
| ▸ | RORC | P51449 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999890 | 0.89 | CYP19A1 (0.56) | CYP19A1CYP3A4CYP3A5 | |
| SCHEMBL4196221 | 0.84 | CYP19A1 (0.55) | CYP19A1CYP3A4 | |
| SCHEMBL5999690 | 0.83 | CYP19A1 (0.45) | CYP19A1RORC | |
| SCHEMBL6000406 | 0.83 | CYP19A1 (0.53) | CYP19A1CYP3A4CYP3A5 | |
| Hydrochloric Acid SCHEMBL20186907 | 0.82 | CYP19A1 (0.53) | CYP19A1CYP3A4 | |
| SCHEMBL5999982 | 0.81 | CYP19A1 (0.42) | CYP19A1CYP3A4 | |
| SCHEMBL5998609 | 0.81 | CYP19A1 (0.43) | CYP19A1CYP3A4 | |
| SCHEMBL30927952 | 0.81 | CYP19A1 (0.71) | CYP19A1RORCCYP3A4CYP3A5 | |
| SCHEMBL29226432 | 0.81 | CYP19A1 (0.71) | CYP19A1RORCCYP3A4CYP3A5 | |
| SCHEMBL29226430 | 0.81 | CYP19A1 (0.71) | CYP19A1RORCCYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058357-A1 | Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke | K AND K BIOSCIENCE, INC. (US) | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058357-A1 | Delta2-1,2,3-triazoline anticonvulsants and their active metabolite analogues, the aminoalkylpyridines, are excitatory amino acid antagonists and antiischemic agents, useful in the treatment of cerebral ischemia resulting from stroke | SIGMAR1, GRM1, GRIN2C | CYP19A1 4624/4885RORC 1392/4885CYP3A4 2214/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.