Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 17/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 17/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 16/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5999642 | 0.80 | AOC3 (0.33) | HTR2AKCNH2SLC6A4 | |
| SCHEMBL6000549 | 0.73 | HTR2A (0.41) | HTR2AKCNH2SLC6A4 | |
| Formic Acid SCHEMBL6000262 | 0.72 | SLC6A4 (0.45) | HTR2AKCNH2SLC6A4 | |
| SCHEMBL5502100 | 0.68 | SLC6A4 (0.44) | HTR2AKCNH2SLC6A4 | |
| SCHEMBL5999798 | 0.67 | SLC6A4 (0.52) | HTR2AKCNH2SLC6A4 | |
| SCHEMBL5498330 | 0.67 | SLC6A4 (0.62) | HTR2AKCNH2SLC6A4 | |
| SCHEMBL29256525 | 0.67 | HDAC3 (0.54) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL13814476 | 0.67 | HDAC3 (0.50) | KCNH2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL11864310 | 0.66 | AOC3 (0.67) | KCNH2SLC6A4 | |
| SCHEMBL24196242 | 0.65 | KDM4E (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | HTR2A 7/4885KCNH2 2331/4885SLC6A4 150/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.