Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 3/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL6000453 | 0.88 | HTR2A (0.37) | PARP1SLC6A4HTR1AHTR2CHTR2A | |
| Formic Acid SCHEMBL6000403 | 0.87 | SLC6A4 (0.47) | PARP1SLC6A4HTR1AHTR2CHTR2A | |
| SCHEMBL6000410 | 0.83 | HTR2A (0.39) | PARP1SLC6A4HTR1AHTR2CHTR2A | |
| SCHEMBL5998743 | 0.77 | MTNR1A (0.37) | SLC6A4HTR1AHTR2CHTR2ASOS1 | |
| Formic Acid SCHEMBL6000448 | 0.76 | HTR2A (0.37) | SLC6A4HTR1AHTR2CHTR2AKCNH2 | |
| Formic Acid SCHEMBL6000422 | 0.76 | SOS1 (0.35) | SLC6A4HTR1AHTR2CHTR2ASOS1 | |
| SCHEMBL6000307 | 0.72 | HTR2C (0.37) | SLC6A4HTR1AHTR2CHTR2ASOS1 | |
| SCHEMBL6000452 | 0.72 | HTR2A (0.41) | SLC6A4HTR1AHTR2CHTR2A | |
| SCHEMBL6000150 | 0.69 | HTR2C (0.38) | SLC6A4HTR1AHTR2CHTR2ASOS1 | |
| Formic Acid SCHEMBL6000270 | 0.68 | FFAR1 (0.39) | SLC6A4HTR2ASOS1KCNH2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | PARP1 3252/4885SLC6A4 150/4885HTR1A 17/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.