Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6000320 | 0.90 | TAAR1 (0.34) | HTR1DTAAR1ADRA1ACYP1A2KDM4E | |
| SCHEMBL5498668 | 0.89 | TAAR1 (0.36) | TAAR1ADRA1ACYP1A2 | |
| SCHEMBL5503316 | 0.85 | TAAR1 (0.35) | TAAR1ADRA1ACYP1A2 | |
| SCHEMBL5502216 | 0.84 | SLC6A4 (0.42) | TAAR1ADRA1A | |
| SCHEMBL5999811 | 0.82 | PNMT (0.35) | TAAR1ADRA1AKDM4ECSNK2A1 | |
| SCHEMBL6000439 | 0.82 | SLC6A4 (0.47) | — | |
| SCHEMBL5497523 | 0.82 | HTR2A (0.43) | TAAR1ADRA1ACYP1A2 | |
| SCHEMBL5502917 | 0.79 | TAAR1 (0.45) | TAAR1ADRA1ACYP1A2 | |
| SCHEMBL5502490 | 0.79 | KDM4E (0.39) | TAAR1ADRA1AKDM4E | |
| SCHEMBL5506301 | 0.78 | TAAR1 (0.36) | TAAR1ADRA1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | PFIZER INC | 2006-03-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060058361-A1 | Therapeutic diphenyl ether ligands | HTR2B, HTR2C, HTR3B | HTR1D 125/4885TAAR1 283/4885ADRA1A 512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.