Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 17/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 6/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2093369 | 0.84 | ATM (0.41) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2095086 | 0.82 | PTGIR (0.55) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2093371 | 0.81 | MEN1 (0.43) | PTGIRATMTDP1L3MBTL1NPSR1 | |
| SCHEMBL2090244 | 0.78 | NPSR1 (0.47) | PTGIRATMTDP1L3MBTL1NPSR1 | |
| SCHEMBL2092436 | 0.77 | PTGIR (0.40) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2090242 | 0.77 | NPSR1 (0.45) | PTGIRATMTDP1L3MBTL1NPSR1 | |
| SCHEMBL2089048 | 0.74 | RIPK1 (0.35) | ALDH1A1HTT | |
| SCHEMBL2090618 | 0.73 | PTGIR (0.39) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2089991 | 0.73 | ATM (0.46) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL2092943 | 0.72 | PTGIR (0.53) | PTGIRPTGDRPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |