Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10287250 | 0.84 | LOXL2 (0.43) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL21275553 | 0.82 | LOXL2 (0.42) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL23692162 | 0.79 | MAOB (0.43) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL800706 | 0.79 | KDM4E (0.44) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL5776749 | 0.76 | FLT3 (0.46) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL8036000 | 0.76 | KDM4E (0.46) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL18909497 | 0.74 | LOXL2 (0.39) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL28018770 | 0.74 | KDM4E (0.44) | CYP2A6FLT3LOXL2MEN1KMT2A | |
| SCHEMBL18768389 | 0.74 | FLT3 (0.49) | FLT3MEN1KMT2AMAOBMAOA | |
| SCHEMBL13713849 | 0.73 | CYP19A1 (0.42) | CYP2A6FLT3LOXL2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |