Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.37 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2097206 | 0.83 | CA2 (0.45) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL6992883 | 0.83 | MAOB (0.46) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2094752 | 0.83 | MAOB (0.46) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL7360353 | 0.80 | MAOB (0.50) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2094754 | 0.79 | PSMB5 (0.49) | MAOBCA2PSMB8PSMB5MAOA | |
| SCHEMBL6002749 | 0.77 | MAOB (0.47) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2092249 | 0.76 | MAOB (0.53) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2097201 | 0.75 | CA2 (0.44) | MAOBCA2PSMB8PSMB5HDAC3 | |
| SCHEMBL9481576 | 0.75 | MAOB (0.45) | MAOBCA2CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2091111 | 0.74 | MAOB (0.41) | MAOBCA2CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |