Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.52 |
| ▸ | FAAH | O00519 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 3/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4864601 | 0.88 | MKNK1 (0.57) | MKNK1FAAHBRS3LIMK1MAPT | |
| SCHEMBL4871319 | 0.85 | MKNK1 (0.55) | MKNK1FAAHBRS3TRPV1 | |
| SCHEMBL4866606 | 0.82 | TRPV1 (0.55) | MKNK1FAAHTRPV1 | |
| SCHEMBL4868405 | 0.82 | TRPV1 (0.59) | MKNK1FAAHTRPV1 | |
| SCHEMBL4872328 | 0.80 | MKNK1 (0.50) | MKNK1FAAHBRS3TRPV1 | |
| SCHEMBL2845073 | 0.79 | MKNK1 (0.54) | MKNK1FAAHBRS3MAPT | |
| SCHEMBL6001517 | 0.79 | TRPV1 (0.59) | TRPV1 | |
| SCHEMBL4870103 | 0.79 | FAAH (0.53) | MKNK1FAAHTRPV1 | |
| SCHEMBL4864825 | 0.78 | MAPT (0.51) | MKNK1FAAHALDH1A1NPSR1LMNA | |
| SCHEMBL4872158 | 0.78 | FAAH (0.73) | MKNK1FAAHTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128710-A1 | Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof | ABBOTT LABORATORIES | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128710-A1 | Antagonists to the vanilloid receptor subtype 1 (VR1) and uses thereof | OPRL1, AVPR1A, AVPR2 | MKNK1 4146/4885FAAH 480/4885KDM1A 1314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.