SCHEMBL60015

SCHEMBL60015

Cc1nn(-c2nc(O)nc(-n3nc(C)c(N=Nc4c(S(C)(=O)=O)cnn4-c4cc(C(=O)O)cc(C(=O)O)c4)c3N)n2)c(N)c1N=Nc1c(S(C)(=O)=O)cnn1-c1cc(C(=O)O)cc(C(=O)O)c1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 6/20 0.35
▸ RAB9A P51151 5/20 0.35
▸ SMN1; SMN2 Q16637 5/20 0.35
▸ NPC1 O15118 4/20 0.35
▸ TDP1 Q9NUW8 4/20 0.35
▸ MAPK1 P28482 4/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ HPGD P15428 2/20 0.35
▸ ALDH1A1 P00352 1/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ ALOX12 P18054 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ GAA P10253 1/20 0.33
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12084072 0.97 MAPT (0.33) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL10052076 0.92 MAPT (0.34) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL4400175 0.92 MAPT (0.34) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL13159225 0.90 — —
SCHEMBL10139526 0.90 — —
SCHEMBL15233454 0.90 — —
SCHEMBL12998664 0.89 MAPT (0.37) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL12998657 0.87 MAPT (0.36) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL13239253 0.86 MAPT (0.32) MAPTRAB9ASMN1; SMN2NPC1TDP1
SCHEMBL58810 0.85 XDH (0.41) MAPTRAB9ASMN1; SMN2NPC1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9315686-B2 Water-based ink for ink-jet recording, water-based ink set for ink-jet recording, ink cartridge, and ink-jet recording method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2016-04-19 — — US disclosed
US-9056997-B2 Ink-jet recording apparatus, ink-jet recording method, recorded matter and composite black BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-06-16 — — US disclosed
US-9033483-B2 Water-based ink set for ink-jet recording, water-based ink, and ink-jet recording method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-05-19 — — US disclosed
US-20150116392-A1 Ink-Jet Recording Apparatus, Ink-Jet Recording Method, Recorded Matter and Composite Black BROTHER KOGYO KABUSHIKI KAISHA (JP) 2015-04-30 — — US disclosed
US-8864297-B2 Water-based ink set for ink-jet recording, ink-jet recording method and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2014-10-21 — — US disclosed
US-20140292901-A1 Water-Based Ink for Ink-Jet Recording, Water-Based Ink Set for Ink-Jet Recording, Ink Cartridge, and Ink-Jet Recording Method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2014-10-02 — — US disclosed
US-20130182054-A1 Water-Based Ink Set For Ink-Jet Recording, Ink-Jet Recording Method and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-07-18 — — US disclosed
US-8460449-B2 Water-based ink set for ink jet recording, ink cartridge, and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-06-11 — — US disclosed
US-20130083145-A1 Water-Based Ink Set for Ink-Jet Recording, Water-Based Ink, and Ink-Jet Recording Method BROTHER KOGYO KABUSHIKI KAISHA (JP) 2013-04-04 — — US disclosed
US-8372190-B2 Ink set, inkjet recording method and recorded material FUJIFILM CORPORATION (JP) 2013-02-12 — — US disclosed
US-8128747-B2 Water-based ink for ink-jet recording, ink cartridge and ink-jet recording apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2012-03-06 — — US disclosed
US-8083341-B2 Thermal ink-jet ink and ink cartridge using the ink CANON KABUSHIKI KAISHA (JP) 2011-12-27 — — US disclosed
US-20110128333-A1 Water-Based Ink Set for Ink Jet Recording, Ink Cartridge, and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2011-06-02 — — US disclosed
US-20100302305-A1 INK SET, INKJET RECORDING METHOD AND RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2010-12-02 — — US disclosed
US-7566362-B2 Ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-07-28 — — US disclosed
US-20090165672-A1 Water-Based Ink for Ink-Jet Recording, Ink Cartridge and Ink-Jet Recording Apparatus BROTHER KOGYO KABUSHIKI KAISHA (JP) 2009-07-02 — — US disclosed
US-7553358-B2 Ink jet ink, ink jet recording method, ink cartridge, recording unit and ink jet recording apparatus CANON KABUSHIKI KAISHA (JP) 2009-06-30 — — US disclosed
US-20090047430-A1 INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2009-02-19 — — US disclosed
US-20080274285-A1 INK JET INK, INK JET RECORDING METHOD, INK CARTRIDGE, RECORDING UNIT AND INK JET RECORDING APPARATUS CANON KABUSHIKI KAISHA (JP) 2008-11-06 — — US disclosed
US-20080151028-A1 THERMAL INK-JET INK AND INK CARTRIDGE USING THE INK CANON KABUSHIKI KAISHA (JP) 2008-06-26 — — US disclosed
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