Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | MAPT | P10636 | 1/20 | 0.74 |
| ▸ | TP53 | P04637 | 2/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.63 |
| ▸ | RAB9A | P51151 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.63 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001770 | 0.88 | ALDH1A1 (0.77) | ALDH1A1MAPTTP53HPGDL3MBTL1 | |
| SCHEMBL2092856 | 0.88 | ALDH1A1 (0.82) | ALDH1A1MAPTTP53HPGDL3MBTL1 | |
| SCHEMBL2092853 | 0.84 | ALDH1A1 (0.82) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL10852085 | 0.84 | ALDH1A1 (0.82) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL1494291 | 0.83 | ALDH1A1 (0.79) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL4542785 | 0.83 | ALDH1A1 (0.85) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL2094905 | 0.83 | ALDH1A1 (0.79) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL7497883 | 0.83 | ALDH1A1 (0.79) | ALDH1A1MAPTHPGDL3MBTL1NPC1 | |
| SCHEMBL8708567 | 0.83 | ALDH1A1 (0.69) | ALDH1A1MAPTTP53HPGDL3MBTL1 | |
| SCHEMBL2097478 | 0.81 | ALDH1A1 (0.66) | ALDH1A1MAPTTP53HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |