Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 9/20 | 0.67 |
| ▸ | DHODH | Q02127 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACACA | Q13085 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ESRRB | O95718 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | ESRRA | P11474 | 1/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29636789 | 0.81 | MAPT (0.71) | ACP1MAPTACACAKDM4EALDH1A1 | |
| SCHEMBL6534502 | 0.81 | TOP1 (0.56) | ACP1MAPTTRPV1ESRRBESR1 | |
| SCHEMBL6534318 | 0.81 | MAPT (0.71) | ACP1MAPTACACAKDM4EALDH1A1 | |
| SCHEMBL8536085 | 0.81 | ACP1 (0.47) | ACP1DHODHIGF1RMAPTKDM4E | |
| SCHEMBL30592743 | 0.80 | DHODH (0.58) | DHODHMAPTACACAKDM4EALDH1A1 | |
| SCHEMBL17688773 | 0.80 | ACP1 (1.00) | ACP1DHODHMAPTACACAKDM4E | |
| SCHEMBL4601706 | 0.80 | DHODH (0.72) | ACP1DHODHMAPTKDM4EALDH1A1 | |
| SCHEMBL29793367 | 0.80 | ACHE (0.61) | DHODHACACAKDM4EALDH1A1LMNA | |
| SCHEMBL785473 | 0.80 | ACHE (0.61) | DHODHACACAKDM4EALDH1A1LMNA | |
| SCHEMBL6001382 | 0.79 | CYP19A1 (0.60) | ACP1DHODHKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | REDDY US THERAPEUTICS, INC. | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128702-A1 | Heterocyclic and bicyclic compounds, compositions and methods | HPSE, ENGASE, UGCG | ACP1 429/4885DHODH 855/4885IGF1R 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.