Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6285097 | 1.00 | KMT2A (0.51) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL6285103 | 1.00 | KMT2A (0.51) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL7621554 | 0.94 | KMT2A (0.54) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL9442349 | 0.91 | MEN1 (0.47) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL3596589 | 0.90 | NFE2L2 (0.42) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL3596587 | 0.90 | NFE2L2 (0.42) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL3596584 | 0.90 | NFE2L2 (0.42) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL13443173 | 0.84 | EGFR (0.38) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL6001894 | 0.84 | KMT2A (0.50) | KMT2AMEN1POLBPKMBLM | |
| SCHEMBL6001892 | 0.84 | KMT2A (0.50) | KMT2AMEN1POLBPKMBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1655280-A1 | Dicarboxylic acid derivates with pharmaceutical properties | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| US-6864287-B1 | Derivatives of dicarboxylic acid having pharmaceutical properties | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-08 | — | — | US | disclosed |