Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.68 |
| ▸ | HTR2C | P28335 | 3/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.54 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.54 |
| ▸ | DRD3 | P35462 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | EED | O75530 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678292 | 0.95 | CHRNA7 (0.67) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL7680070 | 0.95 | CHRNA7 (0.67) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL7680425 | 0.95 | CHRNA7 (0.67) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL6002219 | 0.95 | CHRNA7 (0.66) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL6002202 | 0.90 | CHRNA7 (0.62) | CHRNA7OPRM1OPRK1OPRL1MAOB | |
| SCHEMBL5489875 | 0.89 | HTR2C (0.56) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL20137193 | 0.88 | CHRNA7 (0.80) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL5899579 | 0.88 | CHRNA7 (0.80) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| SCHEMBL9737757 | 0.86 | CHRNA7 (0.77) | CHRNA7HTR2COPRM1OPRK1OPRL1 | |
| Hydrochloric Acid SCHEMBL6421624 | 0.85 | CHRNA7 (0.75) | CHRNA7HTR2COPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020183011-A1 | HTR1D INHIBITORS AND USES THEREOF IN THE TREATMENT OF CANCER | INSTITUT CURIE (FR) | 2020-09-17 | — | — | WO | disclosed |
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| CN-1182847-C | Selective 5-HT1AAntagonists and Selectivity h5-HT1BCombinations of antagonists or partial agonists | — | 2005-01-05 | — | — | CN | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
| CN-1073101-C | Substituted 1,2,3, 4-tetrahydronaphthalene derivatives | ASTRA AB (SE) | 2001-10-17 | — | — | CN | disclosed |
| CN-1279609-A | Selective 5-HT1AAntagonists and Selectivity h 5-HT1BCompositions of antagonists or partial agonists | ASTRAZENECA AB (SE) | 2001-01-10 | — | — | CN | disclosed |
| CN-1270585-A | Substituted 1,2,3, 4-tetrahydronaphthalene derivatives | ASTRA AB (SE) | 2000-10-18 | — | — | CN | disclosed |
| CN-1219170-A | Substituted 1,2,3, 4-tetrahydronaphthalene derivatives | ASTRA AB (SE) | 1999-06-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | CHRNA7 1146/4885HTR2C 792/4885OPRM1 111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.