Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.48 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.43 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.43 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.43 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.43 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.43 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 3/20 | 0.40 |
| ▸ | PPARA | Q07869 | 3/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002074 | 1.00 | NOD2 (0.48) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2346812 | 0.89 | NOD2 (0.52) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2345728 | 0.87 | NOD2 (0.52) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2351246 | 0.86 | NOD2 (0.51) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2346815 | 0.85 | NOD2 (0.49) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2005697 | 0.83 | NOD2 (0.53) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2540534 | 0.82 | NOD2 (0.53) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL2929041 | 0.81 | SMN1; SMN2 (0.47) | NOD2NOD1ACLYALDH1A1PTGDR2 | |
| SCHEMBL8938302 | 0.80 | MAPT (0.50) | NOD2NOD1ACLYPSEN1PSEN2 | |
| SCHEMBL12228548 | 0.80 | NOD2 (0.50) | NOD2NOD1ACLYPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060128783-A1 | Tyrosine kinase inhibitors | DINSMORE CHRISTOPHER J | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060128783-A1 | Tyrosine kinase inhibitors | ABL1, ERBB2, JAK2 | NOD2 2323/4885NOD1 1661/4885ACLY 3643/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.