Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.30 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4260457 | 1.00 | XDH (0.32) | XDHSLC22A12OPRD1EPHX2NSD2 | |
| SCHEMBL4261808 | 0.92 | XDH (0.32) | XDHSLC22A12OPRD1EPHX2NSD2 | |
| SCHEMBL6002296 | 0.89 | NSD2 (0.36) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL3229984 | 0.89 | NSD2 (0.36) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL4262995 | 0.88 | XDH (0.35) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL4261305 | 0.81 | NSD2 (0.36) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL6002181 | 0.81 | NSD2 (0.36) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL4262594 | 0.80 | XDH (0.35) | XDHSLC22A12EPHX2NSD2NLRP3 | |
| SCHEMBL4268513 | 0.79 | TACR2 (0.42) | OPRD1SLC1A2KCNH2 | |
| SCHEMBL4261247 | 0.78 | NSD2 (0.33) | XDHSLC22A12NSD2NLRP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |