Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2092938 | 0.84 | PTGIR (0.52) | L3MBTL1ATMTDP1NPSR1PTGIR | |
| SCHEMBL15518608 | 0.82 | L3MBTL1 (0.61) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL2092800 | 0.82 | TDP1 (0.43) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL2249324 | 0.81 | L3MBTL1 (0.65) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL2093369 | 0.79 | ATM (0.41) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL5494234 | 0.79 | L3MBTL1 (0.63) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL514386 | 0.78 | SMN1; SMN2 (0.53) | L3MBTL1NPSR1KMT2AALDH1A1NPC1 | |
| SCHEMBL2089002 | 0.78 | ATM (0.40) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL4446206 | 0.77 | L3MBTL1 (0.61) | L3MBTL1ATMTDP1NPSR1CHRM3 | |
| SCHEMBL15518997 | 0.77 | L3MBTL1 (0.61) | L3MBTL1ATMTDP1NPSR1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |