Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 5/20 | 0.48 |
| ▸ | TACR1 | P25103 | 5/20 | 0.48 |
| ▸ | TACR3 | P29371 | 5/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HAT1 | O14929 | 7/20 | 0.33 |
| ▸ | EP300 | Q09472 | 7/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | F2R | P25116 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4255229 | 0.94 | TACR2 (0.52) | TACR2TACR1TACR3MCHR1MEN1 | |
| SCHEMBL6002594 | 0.88 | TACR2 (0.48) | TACR2TACR1TACR3MEN1ALDH1A1 | |
| SCHEMBL7666225 | 0.87 | TACR2 (0.54) | TACR2TACR1TACR3MCHR1CA1 | |
| SCHEMBL6668994 | 0.84 | TACR2 (0.64) | TACR2TACR1TACR3 | |
| SCHEMBL7668591 | 0.84 | TACR2 (0.51) | TACR2TACR1TACR3MCHR1HAT1 | |
| SCHEMBL756430 | 0.84 | TACR2 (0.64) | TACR2TACR1TACR3 | |
| SCHEMBL4257657 | 0.81 | TACR2 (0.48) | TACR2TACR1TACR3MEN1ALDH1A1 | |
| SCHEMBL5013875 | 0.76 | TACR2 (0.56) | TACR2TACR1TACR3 | |
| SCHEMBL3226464 | 0.75 | TACR2 (0.46) | TACR2TACR1TACR3MCHR1L3MBTL1 | |
| SCHEMBL4260104 | 0.75 | TACR2 (0.46) | TACR2TACR1TACR3MCHR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |