Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 8/20 | 0.91 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.91 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.91 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.91 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.91 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.91 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4723390 | 0.95 | CYP2D6 (1.00) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL4723343 | 0.89 | CYP1A2 (0.88) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL3407136 | 0.82 | CYP1A2 (0.76) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL6941842 | 0.81 | CYP1A2 (0.73) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL12462292 | 0.80 | CYP1A2 (0.72) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL6575763 | 0.80 | CYP3A4 (0.71) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL14599590 | 0.79 | CYP1A2 (0.70) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL11937116 | 0.78 | CYP3A4 (0.56) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| Methyl Alcohol SCHEMBL10336733 | 0.78 | CYP1A2 (0.69) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL9153965 | 0.78 | RARB (0.71) | CYP2D6CYP1A2CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-5811456-A | TREATMENT OF ALZHEIMER'S DISEASE | LABORATOIRES MAYOLY SPINDLER (FR) | 1998-09-22 | — | — | US | disclosed |