Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 3/20 | 0.70 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.55 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.55 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | QPCT | Q16769 | 1/20 | 0.55 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.55 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.55 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22315192 | 0.93 | TBXAS1 (0.62) | TBXAS1LTA4HCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL10370478 | 0.82 | TBXAS1 (1.00) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL12045305 | 0.81 | TBXAS1 (0.84) | TBXAS1LTA4HPOLBQPCTKMT2A | |
| Hydrochloric Acid SCHEMBL9996050 | 0.81 | TBXAS1 (0.97) | TBXAS1LTA4HKMT2AKDM4EALDH1A1 | |
| SCHEMBL20601860 | 0.81 | TBXAS1 (0.67) | TBXAS1CYP19A1CYP11B1CYP11B2CYP1A2 | |
| Hydrochloric Acid SCHEMBL9996074 | 0.80 | TBXAS1 (0.82) | TBXAS1LTA4HPOLBQPCTKMT2A | |
| SCHEMBL12045307 | 0.80 | TBXAS1 (0.82) | TBXAS1CYP1A2CYP3A4CYP2D6KMT2A | |
| SCHEMBL8995200 | 0.80 | TBXAS1 (0.52) | TBXAS1QPCTKMT2AKDM4EALDH1A1 | |
| SCHEMBL8995204 | 0.80 | TBXAS1 (0.51) | TBXAS1LTA4HCYP11B1QPCTKMT2A | |
| SCHEMBL10476929 | 0.78 | TBXAS1 (0.79) | TBXAS1CYP1A2CYP3A4CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-4006243-A | FUNGICIDE, BACTERICIDE, YEAST | SCHERING AKTIENGESELLSCHAFT (DT) | 1977-02-01 | — | — | US | disclosed |