SCHEMBL6002544

SCHEMBL6002544

O=C(O)CSCSCSCC(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.69
HIF1A Q16665 1/20 0.69
CYP2C19 P33261 2/20 0.50
HSD17B10 Q99714 2/20 0.42
POLB P06746 2/20 0.42
GMNN O75496 1/20 0.42
TP53 P04637 1/20 0.42
MAPT P10636 1/20 0.42
THRB P10828 1/20 0.42
CYP2C9 P11712 1/20 0.42
BLM P54132 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
BHMT Q93088 2/20 0.38
PHGDH O43175 1/20 0.38
FFAR1 O14842 1/20 0.35
HTT P42858 1/20 0.34
MMP12 P39900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1324929 0.97 CYP2D6 (0.73) CYP2D6HIF1ACYP2C19HSD17B10POLB
Hydrochloric Acid SCHEMBL11158845 0.93 CYP2D6 (0.69) CYP2D6HIF1ACYP2C19HSD17B10POLB
SCHEMBL144220 0.82
SCHEMBL2034998 0.82 CYP2D6 (1.00) CYP2D6HIF1ACYP2C19HSD17B10POLB
SCHEMBL10482221 0.81 LMNA (0.62) CYP2D6HIF1ACYP2C19HSD17B10POLB
SCHEMBL14450729 0.81 CYP2D6 (0.52) CYP2D6HIF1ACYP2C19HSD17B10POLB
SCHEMBL11546833 0.79
Ammonia Solution, Strong SCHEMBL28227410 0.79 CYP2D6 (0.92) CYP2D6HIF1ACYP2C19HSD17B10POLB
Ethylene SCHEMBL28577554 0.76 CYP2D6 (0.86) CYP2D6HIF1ACYP2C19HSD17B10POLB
SCHEMBL1313188 0.76 CYP2D6 (0.73) CYP2D6HIF1ACYP2C19HSD17B10POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1640394-A1 POLYOL COMPOUND, TRANSPARENT MOLDED OBJECTS, AND PROCESS FOR PRODUCING TRANSPARENT MOLDED OBJECT HOYA CORPORATION (JP) 2006-03-29 EP disclosed