Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR2 | P21452 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 2/20 | 0.33 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262594 | 0.89 | XDH (0.35) | TACR2TACR1TACR3 | |
| SCHEMBL6002181 | 0.87 | NSD2 (0.36) | TACR2TACR1TACR3 | |
| SCHEMBL4261305 | 0.87 | NSD2 (0.36) | TACR2TACR1TACR3 | |
| SCHEMBL4262995 | 0.82 | XDH (0.35) | TACR2TACR1TACR3 | |
| SCHEMBL3229984 | 0.80 | NSD2 (0.36) | TACR2TACR1TACR3 | |
| SCHEMBL6002296 | 0.80 | NSD2 (0.36) | TACR2TACR1TACR3 | |
| SCHEMBL4261808 | 0.78 | XDH (0.32) | — | |
| SCHEMBL4261683 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL4257621 | 0.71 | TACR2 (0.46) | TACR2TACR1TACR3 | |
| SCHEMBL4262926 | 0.71 | TACR2 (0.46) | TACR2TACR1TACR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636221-A2 | NEW AZETIDINE COMPOUNDS | AstraZeneca AB (SE) | 2006-03-22 | — | — | EP | disclosed |
| WO-2004110344-A2 | NEW AZETIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2004-12-23 | — | — | WO | disclosed |