Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TGM2 | P21980 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138244 | 0.83 | SMN1; SMN2 (0.42) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2097995 | 0.81 | MAPT (0.70) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2097279 | 0.81 | MEN1 (0.55) | MEN1KMT2ATGM2GAAMAPK1 | |
| SCHEMBL482922 | 0.81 | NPC1 (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2088749 | 0.81 | EPHX2 (0.58) | MEN1KMT2ASMN1; SMN2L3MBTL1TGM2 | |
| SCHEMBL5073940 | 0.81 | TGM2 (0.54) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL2092275 | 0.80 | MEN1 (0.60) | MEN1KMT2ASMN1; SMN2MAPTGAA | |
| SCHEMBL19938056 | 0.79 | SMN1; SMN2 (0.67) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL19941030 | 0.79 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT | |
| SCHEMBL3230113 | 0.79 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |