Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090294 | 0.84 | ALDH1A1 (0.65) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL5543435 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL5543439 | 0.81 | ALDH1A1 (0.48) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL25218290 | 0.79 | CYP1A2 (0.60) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL5546774 | 0.79 | CYP1A2 (0.56) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL25250647 | 0.77 | ALDH1A1 (0.72) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL14438051 | 0.77 | ALDH1A1 (0.52) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL5541570 | 0.77 | ALDH1A1 (0.49) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL14438050 | 0.76 | ALDH1A1 (0.57) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 | |
| SCHEMBL2090296 | 0.75 | ALDH1A1 (0.61) | CYP1A2CYP2C19ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |